SCHEMBL2237265

SCHEMBL2237265

C=C(C)C(=O)OCCc1ccc(C(=O)O)c(C(=O)O)c1CCOC(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.36
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2157174 0.94 POLB (0.40) POLBAPEX1HTTTDP1THRB
SCHEMBL3861873 0.94 POLB (0.40) POLBAPEX1HTTTDP1THRB
SCHEMBL1269728 0.90 POLB (0.45) POLBAPEX1HTTTDP1THRB
SCHEMBL8144161 0.90 POLB (0.46) POLBAPEX1HTTTDP1THRB
SCHEMBL8144939 0.89 POLB (0.42) POLBAPEX1HTTTDP1THRB
SCHEMBL815210 0.88 POLB (0.38) POLBAPEX1HTTTDP1THRB
SCHEMBL815209 0.88 POLB (0.38) POLBAPEX1HTTTDP1THRB
SCHEMBL11341100 0.87 POLB (0.50) POLBAPEX1HTTTDP1THRB
SCHEMBL28711621 0.85 POLB (0.36) POLBAPEX1HTTTDP1THRB
SCHEMBL10884576 0.84 THRB (0.40) POLBAPEX1HTTTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150257985-A1 DENTURE TOOTH AND MATERIAL HYBRID CERAMIC LLC 2015-09-17 US claimed
US-11034922-B2 Cleaning agent composition THE YOKOHAMA RUBBER CO., LTD. 2021-06-15 US disclosed
EP-3045506-B1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHINETSU CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20190264145-A1 Cleaning Agent Composition SIKA TECHNOLOGY AG (CH) 2019-08-29 US disclosed
US-9441133-B2 Organic resin laminate, methods of making and using the same, and articles comprising the same EXATEC, LLC (US) 2016-09-13 US disclosed
US-20160208132-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-07-21 US disclosed
US-20150125707-A1 TITANIA-CONTAINING COATING COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-07 US disclosed
US-8809438-B2 UV-shielding coating composition and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-19 US disclosed
US-20140170400-A1 ORGANIC RESIN LAMINATE, METHODS OF MAKING AND USING THE SAME, AND ARTICLES COMPRISING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-19 US disclosed
US-8592521-B2 Method for preparing a primer composition and coated product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-11-26 US disclosed
US-4855475-A (Meth)acrylic esters of phosphoric acid ester dihalides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-08 US disclosed
EP-0294785-A2 Magenta dye-forming coupler FUJI PHOTO FILM CO., LTD. (JP) 1988-12-14 EP disclosed
EP-0273390-A2 Radiation curable resin composition for use in magnetic recording media MITSUBISHI RAYON CO., LTD. (JP) 1988-07-06 EP disclosed
US-4696955-A IN SITU FILLERS FOR TEETH BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) 1987-09-29 US disclosed
US-4670576-A DENTISTRY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-02 US disclosed
EP-0193643-A2 Curable resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-09-10 EP disclosed
EP-0042251-B1 VINYL CHLORIDE PLASTISOL COMPOSITIONS, RESINS SUITABLE FOR USE THEREIN, AND SHAPED STRUCTURES MADE THEREFROM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-05 EP disclosed
US-4429071-A FLOOR AND WALL COVERINGS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-31 US disclosed
EP-0042251-A1 Vinyl chloride plastisol compositions, resins suitable for use therein, and shaped structures made therefrom SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-23 EP disclosed
US-4297099-A BY PENETRATION AND CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed