Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 8/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230253 | 0.78 | RAB9A (0.51) | TRPV4GRM1GRM5ALDH1A1CYP1A2 | |
| SCHEMBL4391482 | 0.71 | MAPK1 (0.70) | GRM1GRM5POLBKDM4EMEN1 | |
| SCHEMBL30089875 | 0.70 | KCNH2 (0.57) | GRM1POLBKCNH2HRH3ALDH1A1 | |
| SCHEMBL29110398 | 0.70 | KCNH2 (0.57) | GRM1POLBKCNH2HRH3ALDH1A1 | |
| SCHEMBL28924659 | 0.69 | KCNH2 (0.56) | GRM1GRM5POLBKCNH2HRH3 | |
| SCHEMBL30149445 | 0.69 | KCNH2 (0.56) | GRM1GRM5POLBKCNH2HRH3 | |
| SCHEMBL29110429 | 0.67 | HRH3 (0.57) | GRM1POLBKCNH2HRH3ALDH1A1 | |
| SCHEMBL7179390 | 0.67 | EGFR (0.58) | GRM1GRM5POLBHPGDTSHR | |
| SCHEMBL28924682 | 0.66 | HRH3 (0.56) | GRM1GRM5POLBKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL11398762 | 0.66 | MAT2A (0.54) | POLBKCNH2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903344-B1 | Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin | SHISEIDO CO LTD (JP) | 2011-01-26 | — | — | EP | disclosed |