Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | WEE1 | P30291 | 4/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040982 | 0.78 | TRPV4 (0.50) | TRPV4ALDH1A1GRM1CYP1A2CYP3A4 | |
| SCHEMBL4827730 | 0.76 | MAPK14 (0.45) | USP2CASP1CASP7 | |
| SCHEMBL20886963 | 0.69 | RAB9A (1.00) | RAB9ADRD2DRD3MAPTHTR1A | |
| SCHEMBL5256633 | 0.68 | MCHR1 (0.73) | MCHR1DRD3HTR2CCYP3A4 | |
| SCHEMBL5429660 | 0.66 | GRM1 (0.52) | RAB9AGRM1GRM5 | |
| SCHEMBL8245138 | 0.66 | GRM1 (0.60) | RAB9AALDH1A1GRM1GRM5 | |
| SCHEMBL23131531 | 0.66 | DRD2 (0.46) | DRD2DRD3ALDH1A1MAPTHTR1A | |
| SCHEMBL28311804 | 0.65 | ADRA2C (0.53) | DRD2DRD3MAPT | |
| SCHEMBL8247056 | 0.65 | GRM1 (0.78) | ALDH1A1GRM1GRM5 | |
| SCHEMBL8245805 | 0.65 | GRM1 (0.74) | ALDH1A1GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7258224-A | — | — | None | — | — | JP | disclosed |
| JP-H07258224-A | BICYCLIC COMPOUND | DAI ICHI SEIYAKU CO LTD | 1995-10-09 | — | — | JP | disclosed |