SCHEMBL10409869

SCHEMBL10409869

Cc1ccc(S(=O)(=O)ON2C(=O)c3ccc(C(=O)Cl)cc3C2=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.62
KDM4E B2RXH2 9/20 0.54
ALDH1A1 P00352 9/20 0.54
HPGD P15428 6/20 0.54
KMT2A Q03164 6/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 8/20 0.48
F2 P00734 4/20 0.47
XBP1 P17861 2/20 0.46
HTT P42858 2/20 0.46
POLB P06746 2/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5556363 0.90 VDR (0.65) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL14620102 0.88 VDR (0.63) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL13632614 0.86 VDR (0.60) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL13622414 0.84 VDR (0.58) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL5556208 0.83 VDR (0.77) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL14620103 0.81 VDR (0.68) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL13622410 0.81 VDR (0.54) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL3822702 0.79 VDR (0.68) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL12534846 0.78 LMNA (0.56) VDRKDM4EALDH1A1HPGDKMT2A
SCHEMBL14620101 0.77 VDR (0.67) VDRKDM4EALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4957988-A Process and polymers for the production of images CIBA-GEIGY CORPORATION (US) 1990-09-18 US disclosed