Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 7/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583099 | 0.80 | CYP2C9 (0.33) | KMT2ACYP2C9RORCRENPOLB | |
| SCHEMBL2683799 | 0.77 | KMT2A (0.35) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL2683870 | 0.77 | KMT2A (0.35) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL5505093 | 0.75 | CYP2C9 (0.33) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL1041031 | 0.75 | CYP2C9 (0.33) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL2683168 | 0.74 | KMT2A (0.38) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL2683813 | 0.73 | KMT2A (0.36) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL1036350 | 0.73 | KMT2A (0.37) | KMT2ACYP2C9RORCRENMEN1 | |
| SCHEMBL3907620 | 0.73 | PKM (0.39) | KMT2ACYP2C9RENPOLB | |
| SCHEMBL2682464 | 0.73 | KMT2A (0.36) | KMT2ACYP2C9RORCRENMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |