Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 6/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041031 | 1.00 | CYP2C9 (0.33) | CYP2C9RENRORCKMT2APOLB | |
| SCHEMBL4959527 | 0.95 | REN (0.32) | CYP2C9RENRORCKMT2A | |
| SCHEMBL1517996 | 0.94 | REN (0.32) | CYP2C9RENRORCKMT2A | |
| SCHEMBL2918847 | 0.94 | FKBP1A (0.33) | CYP2C9RENRORCKMT2APOLB | |
| SCHEMBL1040945 | 0.94 | LMNA (0.32) | CYP2C9RENRORCPOLB | |
| SCHEMBL1517809 | 0.92 | REN (0.31) | CYP2C9REN | |
| SCHEMBL2389129 | 0.90 | REN (0.31) | REN | |
| SCHEMBL4959467 | 0.87 | CYP2C9 (0.36) | CYP2C9RENRORCKMT2APOLB | |
| SCHEMBL2920405 | 0.86 | FKBP1A (0.36) | CYP2C9KMT2A | |
| SCHEMBL2920447 | 0.85 | RORC (0.36) | CYP2C9RORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863803-A2 | SUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103277-A2 | 2 , 4 , 5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-10-05 | — | — | WO | disclosed |