Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494015 | 0.91 | HTR6 (0.53) | LMNAGAAKMT2ACASP1PTGS2 | |
| SCHEMBL10709549 | 0.89 | HTR6 (0.50) | LMNAPTGS2CA1CA2HTR6 | |
| SCHEMBL28394438 | 0.84 | NCOA1 (0.44) | LMNAGAAKMT2AHTR6POLB | |
| SCHEMBL30016251 | 0.84 | NCOA1 (0.44) | LMNAGAAKMT2AHTR6POLB | |
| SCHEMBL146565 | 0.84 | CASP1 (0.50) | LMNAGAAKMT2ACASP1PTGS2 | |
| SCHEMBL502864 | 0.84 | CASP1 (0.50) | LMNAGAAKMT2ACASP1PTGS2 | |
| SCHEMBL5919466 | 0.84 | SLC22A12 (0.42) | CA1CA2CA12CA7CA13 | |
| Ammonia Solution, Strong SCHEMBL502557 | 0.82 | CASP1 (0.49) | LMNAGAAKMT2ACASP1PTGS2 | |
| SCHEMBL11599660 | 0.82 | CASP1 (0.49) | LMNAGAAKMT2ACASP1PTGS2 | |
| SCHEMBL30444967 | 0.82 | MAPT (0.50) | LMNAGAAKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931541-A | ETHYNYLATION OF HALOGENATED BENZOXAZINONE FOLLOWED BY CONDENSATION WITH AROMATIC PRIMARY DIAMINE AND BULK POLY; HEAT RESISTANCE; ADHESIVES, ELECTRONICS | CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) | 1990-06-05 | — | — | US | claimed |
| EP-0330544-A1 | Thermosetting quinazolone resins, their preparation, and their applications | CENTRE D'ETUDES DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) | 1989-08-30 | — | — | EP | claimed |
| US-4931541-A | ETHYNYLATION OF HALOGENATED BENZOXAZINONE FOLLOWED BY CONDENSATION WITH AROMATIC PRIMARY DIAMINE AND BULK POLY; HEAT RESISTANCE; ADHESIVES, ELECTRONICS | CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) | 1990-06-05 | — | — | US | disclosed |
| EP-0330544-A1 | Thermosetting quinazolone resins, their preparation, and their applications | CENTRE D'ETUDES DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) | 1989-08-30 | — | — | EP | disclosed |