SCHEMBL146565

SCHEMBL146565

O=S(=O)(c1ccccc1Oc1ccccc1)c1ccccc1Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.50
HTR6 P50406 1/20 0.50
GAA P10253 2/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
PTGS2 P35354 1/20 0.46
TSHR P16473 2/20 0.46
LTA4H P09960 1/20 0.46
CTNNB1 P35222 1/20 0.46
MMP2 P08253 1/20 0.45
MMP3 P08254 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP12 P39900 1/20 0.45
MMP13 P45452 1/20 0.45
MMP14 P50281 1/20 0.45
MMP16 P51512 1/20 0.45
HTT P42858 2/20 0.44
RIPK1 Q13546 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502864 1.00 CASP1 (0.50) CASP1HTR6GAALMNAKMT2A
Ammonia Solution, Strong SCHEMBL502557 0.98 CASP1 (0.49) CASP1HTR6GAALMNAKMT2A
SCHEMBL11599660 0.98 CASP1 (0.49) CASP1HTR6GAALMNAKMT2A
SCHEMBL9323437 0.90 HTR6 (0.65) CASP1HTR6GAALMNAKMT2A
SCHEMBL11600047 0.89 CASP1 (0.43) CASP1HTR6GAALMNAKMT2A
SCHEMBL11186053 0.87 MMP13 (0.61) CASP1HTR6LMNAPTGS2MMP2
Biphenyl SCHEMBL1071653 0.85 HTR6 (0.59) CASP1HTR6KMT2APTGS2MMP2
SCHEMBL28656015 0.85 PTGS2 (0.54) CASP1HTR6GAALMNAKMT2A
SCHEMBL10411384 0.84 LMNA (0.43) CASP1HTR6GAALMNAKMT2A
SCHEMBL30340391 0.84 NCOA1 (0.51) CASP1HTR6GAAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866110-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-10-20 EP claimed
US-5374469-A Using thermoplastic polyimide resin showing adhesive properties by press bending by heating, using low-linear expansion polyimide NITTO DENKO CORPORATION (JP) 1994-12-20 US claimed
EP-0533198-A2 Flexible printed substrate NITTO DENKO CORPORATION (JP) 1993-03-24 EP claimed
US-4584364-A Phenolic-capped imide sulfone resins THE BOEING COMPANY (US) 1986-04-22 US claimed
US-4499258-A HEAT-RESISTANT LAMINATES; FILMS;HIGH STRENGTH THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1985-02-12 US claimed
US-4414380-A IN POLYCARBONYLS UOP INC. (US) 1983-11-08 US claimed
US-20230255943-A1 MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE THE UNIVERSITY OF BIRMINGHAM (GB) 2023-08-17 US disclosed
EP-4171553-A1 MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE The University Of Birmingham (GB) 2023-05-03 EP disclosed
CN-116033902-A Methods of treating spinal cord injury or related nerve tissue injury 伯明翰大学 2023-04-28 CN disclosed
WO-2021260387-A1 MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE THE UNIVERSITY OF BIRMINGHAM (GB) 2021-12-30 WO disclosed
EP-2438106-B1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS BOEING CO (US) 2015-03-11 EP disclosed
CN-102307933-B Oligomers with diphenylethynyl endcaps BOEING CO 2014-05-07 CN disclosed
EP-2438106-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS The Boeing Company (US) 2012-04-11 EP disclosed
EP-0305882-A2 Amideimide oligomers & blends THE BOEING COMPANY (US) 1989-03-08 EP disclosed
US-4764566-A HIGH STRENGTH ALLIED-SIGNAL INC. (US) 1988-08-16 US disclosed
US-4684714-A Method for making polyimide oligomers THE BOEING COMPANY (US) 1987-08-04 US disclosed
US-4414380-A IN POLYCARBONYLS UOP INC. (US) 1983-11-08 US disclosed
US-4414380-A IN POLYCARBONYLS UOP INC. (US) 1983-11-08 US disclosed
US-4203922-A Fluorinated aromatic diamine TRW INC. (US) 1980-05-20 US disclosed
US-4111906-A POLYIMIDES PREPARED FROM PERFLUOROISOPROPYLIDENE DIAMINE TRW INC. (US) 1978-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255943-A1 MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE MMP12, MMP13, MMP10 CASP1 209/4885HTR6 2917/4885GAA 635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.