SCHEMBL10411575

SCHEMBL10411575

OCCSc1nc(Cl)nc(Cl)n1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALPL P05186 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
ABCB1 P08183 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
EPHX2 P34913 1/20 0.32
ADORA1 P30542 2/20 0.31
HSP90AA1 P07900 1/20 0.31
GRM1 Q13255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9367317 0.85 ALDH1A1 (0.47) ALDH1A1ALOX15TSHR
SCHEMBL11354287 0.76 ALDH1A1 (0.44) ALDH1A1ALOX15TSHRALPLSMN1; SMN2
SCHEMBL17564529 0.76 ALDH1A1 (0.38) ALDH1A1ALOX15TSHR
SCHEMBL17564553 0.76 ALOX15 (0.38) ALDH1A1ALOX15TSHRSMN1; SMN2
SCHEMBL17564532 0.73 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL17564531 0.73 ALDH1A1 (0.35) ALDH1A1ALOX15TSHRSMN1; SMN2
SCHEMBL9723525 0.73 USP2 (0.46) ALDH1A1ALOX15TSHRSMN1; SMN2
SCHEMBL28837274 0.72 LMNA (0.44) ALDH1A1TSHRALPLSMN1; SMN2
SCHEMBL28837293 0.72 LMNA (0.44) ALDH1A1TSHRALPLSMN1; SMN2
SCHEMBL28952697 0.72 LMNA (0.44) ALDH1A1TSHRALPLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939243-A Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed