Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636165 | 0.87 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2GAAHTT | |
| SCHEMBL9636030 | 0.84 | MAPK1 (0.55) | ALDH1A1LMNAGAAHTTHIF1A | |
| SCHEMBL15677164 | 0.82 | AR (0.62) | LMNASMN1; SMN2CYP3A4GAAHTT | |
| SCHEMBL1101535 | 0.82 | HTT (0.61) | ALDH1A1LMNASMN1; SMN2GAAHTT | |
| SCHEMBL10078135 | 0.82 | HTT (0.61) | ALDH1A1LMNACYP3A4GAAHTT | |
| SCHEMBL10412598 | 0.80 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2CYP3A4GAAHTT | |
| SCHEMBL1101566 | 0.77 | HTT (0.55) | ALDH1A1LMNASMN1; SMN2GAAHTT | |
| SCHEMBL12403146 | 0.76 | GAA (0.64) | ALDH1A1LMNASMN1; SMN2GAAHTT | |
| SCHEMBL7879426 | 0.76 | CYP3A4 (0.61) | ALDH1A1LMNASMN1; SMN2CYP3A4GAA | |
| SCHEMBL31414645 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNAGAAHIF1ANCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239536-B1 | LUBRICANT COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| EP-0239536-A2 | Lubricant compositions | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | claimed |