Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.55 |
| ▸ | HTR1D | P28221 | 6/20 | 0.55 |
| ▸ | HTR1B | P28222 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281097 | 0.88 | HTR1A (0.50) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL11243420 | 0.88 | HTR1A (0.69) | HTR1A | |
| Hydrochloric Acid SCHEMBL11224419 | 0.87 | HTR1A (0.68) | HTR1A | |
| SCHEMBL10413747 | 0.87 | HTR1B (0.48) | HTR1AHTR1DHTR1BMAPTMAPK1 | |
| SCHEMBL10413625 | 0.86 | HTR1A (0.56) | HTR1AHTR1B | |
| SCHEMBL10412926 | 0.86 | HTR1A (0.58) | HTR1AHTR1B | |
| SCHEMBL10413248 | 0.86 | HTR1A (0.58) | HTR1AHTR1B | |
| SCHEMBL10413236 | 0.86 | HTR1A (0.58) | HTR1AHTR1B | |
| SCHEMBL10414181 | 0.86 | HTR1A (0.58) | HTR1AHTR1B | |
| SCHEMBL10413220 | 0.86 | HTR1A (0.58) | HTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |