Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 17/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412044 | 0.94 | ALKBH5 (0.47) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10390963 | 0.94 | ALKBH5 (0.56) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10412743 | 0.88 | ALKBH5 (0.50) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10412787 | 0.84 | ALKBH5 (0.51) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL8751526 | 0.84 | ALKBH5 (0.56) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL67421 | 0.82 | ALKBH5 (0.66) | ALKBH5ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5162317 | 0.80 | ALKBH5 (0.46) | ALKBH5ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11228689 | 0.80 | ALKBH5 (0.52) | ALKBH5ALDH1A1MAPT | |
| SCHEMBL693103 | 0.79 | ALKBH5 (0.64) | ALKBH5ALDH1A1TDP1HSD17B10 | |
| SCHEMBL691280 | 0.78 | ALKBH5 (0.57) | ALKBH5ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906738-A | Water-soluble phenyl- or naphthyl-azo-carboxypyrazolone compounds, containing a fiber-reactive group with a chloratriazinyl moiety and a group of the vinylsulfone series in the pyrazolone coupling component, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |