SCHEMBL67421

SCHEMBL67421

O=C(O)c1cc(=O)n(-c2ccc(S(=O)(=O)O)cc2)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 17/20 0.66
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10654204 0.92 ALDH1A1 (0.60) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL9176966 0.87 ALKBH5 (0.61) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL692998 0.87 ALKBH5 (0.64) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL11437033 0.87 ALKBH5 (0.49) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL1265785 0.86 ALKBH5 (0.55) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL11043787 0.84 ALKBH5 (0.49) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL693103 0.84 ALKBH5 (0.64) ALKBH5ALDH1A1TDP1
SCHEMBL11807463 0.83 ALKBH5 (0.51) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL10413159 0.82 ALKBH5 (0.50) ALKBH5KDM4EALDH1A1MAPTKMT2A
SCHEMBL9619302 0.82 ALKBH5 (0.58) ALKBH5KDM4EALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946536-A Preparation process of gray black reactive dye 浙江劲光实业股份有限公司 2024-04-30 CN claimed
CN-114044803-B Acetyl hexapeptide-1 derivative and application thereof 浙江湃肽生物有限公司深圳分公司 2022-04-12 CN claimed
CN-114044803-A Acetyl hexapeptide-1 derivative and application thereof 浙江湃肽生物有限公司深圳分公司 2022-02-15 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
EP-2421501-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF The Procter & Gamble Company (US) 2012-02-29 EP claimed
US-7988740-B2 Keratin dyeing compositions comprising a radical scavenger and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-08-02 US claimed
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof NOXELL CORPORATION 2011-02-17 US claimed
WO-2010123863-A2 KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2010-10-28 WO claimed
EP-0062183-B1 RESIST PRINTING PROCESS BAYER AG (DE) 1986-07-02 EP claimed
EP-0062183-A2 Resist printing process BAYER AG (DE) 1982-10-13 EP claimed
US-4169831-A HAVING 1 OR 2 SULFONIC ACID GROUPS, LEATHER PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1979-10-02 US claimed
US-4081437-A Water soluble polyazo dyestuffs PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-03-28 US claimed
JP-60225061-A None JP disclosed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US disclosed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP disclosed
US-12036208-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2024-07-16 US disclosed
US-4019966-A Method of amperometric determination of the concentration of arendiazonium salts VYZKUMNY USTAV ORGANICKYCH SYNTEX (CS) 1977-04-26 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036208-B2 Methods for treating neurodegenerative disorders NLN, CLN6, SNCA ALKBH5 2454/4885KDM4E 3838/4885ALDH1A1 3244/4885
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof KRT18, LPO, CYB5R3 ALKBH5 413/4885KDM4E 841/4885ALDH1A1 326/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 ALKBH5 1080/4885KDM4E 2928/4885ALDH1A1 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.