Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412611 | 0.91 | CCNT1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10413303 | 0.86 | KMT2A (0.44) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10413402 | 0.84 | HSD17B10 (0.56) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL9731576 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL5258973 | 0.81 | KMT2A (0.57) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL2089304 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10414001 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6780213 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10471178 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10413071 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |