Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412678 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL10413402 | 0.87 | HSD17B10 (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10413898 | 0.84 | ADRB2 (0.44) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL10413899 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL4306583 | 0.80 | KMT2A (0.60) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL29576844 | 0.80 | KMT2A (0.60) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL9730924 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL10577000 | 0.80 | KMT2A (0.54) | KDM4EALDH1A1ADRB2HPGDHSD17B10 | |
| SCHEMBL10414001 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7862768 | 0.78 | TOP2A (0.52) | KDM4EALDH1A1ADRB2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |