Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414001 | 0.92 | KDM4E (0.46) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9731576 | 0.87 | KDM4E (0.49) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10413899 | 0.84 | ALDH1A1 (0.43) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10413895 | 0.83 | LMNA (0.49) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10578229 | 0.81 | HSD17B10 (0.59) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7128071 | 0.78 | KMT2A (0.76) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10412678 | 0.77 | KDM4E (0.51) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL10575415 | 0.76 | KMT2A (0.67) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10412667 | 0.76 | LMNA (0.49) | HSD17B10KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10517657 | 0.76 | HPGD (0.59) | HSD17B10KDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |