SCHEMBL10414031

SCHEMBL10414031

CCC(C)(O)c1cccc(C(C)(O)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ACHE P22303 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
RAB9A P51151 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
LMNA P02545 1/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
AR P10275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599298 0.94 ESR1 (0.39) ESR1ESR2HDAC4HDAC2HDAC8
SCHEMBL7117971 0.90 CES2 (0.44) POLBLMNA
SCHEMBL2399948 0.87 ESR1 (0.42) ESR1ESR2ACHEGABRA1GABRB2
SCHEMBL7122141 0.87 LMNA (0.49) ACHECYP2C9LMNA
SCHEMBL13815889 0.87 ESR1 (0.42) ESR1ESR2ACHEGABRA1GABRB2
SCHEMBL14196688 0.86 TSHR (0.48) NPC1RAB9A
SCHEMBL19204248 0.86 SCN5A (0.47)
SCHEMBL31292746 0.86 RIPK1 (0.42) NPC1RAB9ALMNA
SCHEMBL30472160 0.86 KCNN4 (0.46) HDAC2ACHE
SCHEMBL9906173 0.86 SCN5A (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4968759-A Phenolic polymer and production thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-11-06 US claimed
US-4897438-A BLEND WITH A PHENOLIC RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-01-30 US disclosed
EP-0122213-B1 PROCESS FOR MAKING POLYMERIC COMPOUNDS PREPARED FROM DIPHENYLAMINE AND DIALKYLALKENYLBENZENE OR DIHYDROXYALKYLBENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-03-22 EP disclosed
EP-0122865-B1 POLYMERS WITH POLYMERIC ANTIOXIDANTS PREPARED FROM DIPHENYLAMINE AND DIALKYLALKENYLBENZENE OR DIHYDROXYALKYLBENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-03-01 EP disclosed
EP-0117831-B1 STABILIZED POLYESTER COMPOSITIONS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-04-22 EP disclosed
US-4537952-A Polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-27 US disclosed
EP-0122865-A1 Polymers with polymeric antioxidants prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-24 EP disclosed
EP-0122213-A1 Process for making polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-17 EP disclosed
EP-0117831-A1 Stabilized polyester compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-09-05 EP disclosed
US-4463170-A OXIDATION RESISTANCE STABILIZERS FOR POLYAMINES, POLYPHENYL RESINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-07-31 US disclosed
US-4417017-A Polymeric antioxidants prepared from diphenyalmine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-22 US disclosed
US-4414348-A POLYMERIC DIPHENYLAMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-08 US disclosed