Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | UQCRB | P14927 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL27583791 | 0.85 | TSHR (0.52) | TSHRCYP3A4PIK3CAHSD17B10RAB9A | |
| Sulfuric Acid SCHEMBL10414234 | 0.83 | IDO1 (0.50) | CYP3A4HSD17B10RAB9ANPC1KDM4E | |
| Sulfuric Acid SCHEMBL5159122 | 0.83 | IDO1 (0.50) | CYP3A4HSD17B10RAB9ANPC1KDM4E | |
| Hydroquinone SCHEMBL11114705 | 0.79 | ALDH1A1 (0.57) | CYP3A4HSD17B10RAB9ANPC1KDM4E | |
| Sulfuric Acid SCHEMBL5843676 | 0.78 | HDAC3 (0.44) | CYP3A4HSD17B10RAB9ANPC1KDM4E | |
| Sulfuric Acid SCHEMBL28381193 | 0.77 | GAA (0.46) | CYP3A4HSD17B10RAB9ANPC1KDM4E | |
| SCHEMBL71383 | 0.76 | — | — | |
| SCHEMBL29975466 | 0.76 | — | — | |
| Sulfuric Acid SCHEMBL8638504 | 0.74 | TSHR (0.70) | TSHRCYP3A4PIK3CAHSD17B10RAB9A | |
| Water SCHEMBL28781371 | 0.74 | CYP3A4 (0.62) | TSHRCYP3A4PIK3CAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977422-A | Apparatus for transporting flat sheets, especially photosensitive sheet materials | VISICON, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| US-4845019-A | Method for exposing and developing photosensitive materials | VISICON LABORATORIES, INC. (US) | 1989-07-04 | — | — | US | disclosed |