Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5159122 | 0.92 | IDO1 (0.50) | GAAKMT2AKDM4EMAPTTDP1 | |
| Sulfuric Acid SCHEMBL10414234 | 0.92 | IDO1 (0.50) | GAAKMT2AKDM4EMAPTTDP1 | |
| Hydroquinone SCHEMBL11114705 | 0.87 | ALDH1A1 (0.57) | GAAKMT2AKDM4EMAPTTDP1 | |
| SCHEMBL457878 | 0.82 | — | — | |
| Sulfuric Acid SCHEMBL30385174 | 0.80 | HTR6 (0.52) | GAAKMT2AKDM4EMAPTTDP1 | |
| Hydrogen Sulfide SCHEMBL28274988 | 0.80 | IDO1 (0.52) | GAAKMT2AKDM4EMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL11322195 | 0.80 | IDO1 (0.52) | GAAKMT2AKDM4EMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL11320051 | 0.80 | IDO1 (0.52) | GAAKMT2AKDM4EMAPTTDP1 | |
| SCHEMBL1668337 | 0.79 | GAA (0.56) | GAAKMT2AKDM4EMAPTTDP1 | |
| Sulfuric Acid SCHEMBL9615897 | 0.79 | GAA (0.56) | GAAKMT2AKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118891053-A | Pharmaceutical preparation and application thereof | 苏中药业集团股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118634232-A | Application of pharmaceutical composition in preparation of medicine for treating and/or preventing skin diseases | 苏中药业集团股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118634233-A | Application of pharmaceutical composition in preparation of medicine for promoting wound healing | 苏中药业集团股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-117582459-A | Application of flos Abelmoschi Manihot extract in preparing medicine for treating and/or preventing ulcer diseases | 苏中药业集团股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-108498546-B | Traditional Chinese medicine composition for preventing or treating ulcerative colitis canceration and application | 闫珺 | 2020-03-10 | — | — | CN | disclosed |