SCHEMBL10414731

SCHEMBL10414731

CC(=O)c1ccccc1C=O.[Cr]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
ERN1 O75460 3/20 0.43
TLR2 O60603 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
CA1 P00915 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1484113 0.98 LMNA (0.52) LMNAMEN1THRBBLMKMT2A
Benzene SCHEMBL28952313 0.96 LMNA (0.50) LMNAMEN1THRBBLMKMT2A
SCHEMBL10415655 0.96 LMNA (0.50) LMNAMEN1THRBBLMKMT2A
Alanine SCHEMBL17848081 0.84 LMNA (0.39) LMNAMEN1THRBBLMKMT2A
SCHEMBL8588159 0.82 LMNA (0.45) LMNAMEN1KMT2ATDP1ALDH1A1
SCHEMBL8579455 0.82 LMNA (0.41) LMNAMEN1KMT2AALDH1A1KDM4E
SCHEMBL4285512 0.82 MEN1 (0.44) LMNAMEN1THRBBLMKMT2A
SCHEMBL5173448 0.82 ERN1 (0.44) LMNAMEN1THRBBLMKMT2A
SCHEMBL8120539 0.81 ERN1 (0.57) LMNAMEN1THRBBLMKMT2A
Salicyladehyde SCHEMBL5813747 0.80 TRIM24 (0.67) LMNAMEN1THRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4913843-A AIR DRYABLE COATING OF THERMOPARTICULATING COMPOUND AND RESIN CARRIER IN ORGANIC SOLVENT WESTINGHOUSE ELECTRIC CORP. (US) 1990-04-03 US disclosed