SCHEMBL4285512

SCHEMBL4285512

CC(=O)c1ccccc1-c1ccccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
KDM4C Q9H3R0 1/20 0.41
ERN1 O75460 4/20 0.39
TLR2 O60603 1/20 0.38
TLR1 Q15399 1/20 0.38
TLR6 Q9Y2C9 1/20 0.38
DAPK3 O43293 1/20 0.38
JAK2 O60674 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
PAK4 O96013 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285509 0.84 PDK2 (0.44) MEN1LMNATHRBBLMKMT2A
SCHEMBL1484113 0.84 LMNA (0.52) MEN1LMNATHRBBLMKMT2A
SCHEMBL978600 0.83 KDM4C (0.50) MEN1LMNAKMT2AALDH1A1KDM4C
SCHEMBL547698 0.82 LMNA (0.53) MEN1LMNATHRBBLMKMT2A
SCHEMBL29955778 0.82 LMNA (0.53) MEN1LMNATHRBBLMKMT2A
SCHEMBL10415655 0.82 LMNA (0.50) MEN1LMNATHRBBLMKMT2A
SCHEMBL10414731 0.82 LMNA (0.50) MEN1LMNATHRBBLMKMT2A
Benzene SCHEMBL28952313 0.82 LMNA (0.50) MEN1LMNATHRBBLMKMT2A
SCHEMBL21556360 0.81 LMNA (0.44) MEN1LMNATHRBBLMKMT2A
SCHEMBL24595466 0.80 MEN1 (0.59) MEN1LMNATHRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3270196-A1 COMPOSITION KIT, LAYERED BODY AND METHOD FOR MANUFACTURING SAME, AND BANDPASS FILTER FUJI-FILM Corporation (JP) 2018-01-17 EP disclosed
US-20090088444-A1 Substituted phenanthrene diketo acids and uses therefor BUOLAMWINI JOHN K 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088444-A1 Substituted phenanthrene diketo acids and uses therefor WEE1, WEE2, HADHB MEN1 2365/4885LMNA 2374/4885THRB 3870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.