Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484113 | 0.84 | LMNA (0.52) | ERN1TLR2TLR1TLR6TDP1 | |
| SCHEMBL20616689 | 0.83 | G6PD (0.36) | THRBLMNAKMT2ACA1CA2 | |
| SCHEMBL25273832 | 0.82 | G6PD (0.57) | ERN1TDP1THRBMEN1LMNA | |
| SCHEMBL27504839 | 0.82 | ALDH1A1 (0.42) | ERN1TDP1THRBMEN1LMNA | |
| Benzene SCHEMBL28952313 | 0.82 | LMNA (0.50) | ERN1TLR2TLR1TLR6TDP1 | |
| SCHEMBL10415655 | 0.82 | LMNA (0.50) | ERN1TLR2TLR1TLR6TDP1 | |
| SCHEMBL10414731 | 0.82 | LMNA (0.50) | ERN1TLR2TLR1TLR6TDP1 | |
| SCHEMBL3498784 | 0.81 | G6PD (0.46) | THRBLMNAKMT2ACA1CA2 | |
| Ammonia Solution, Strong SCHEMBL27817253 | 0.81 | G6PD (0.55) | ERN1TDP1THRBMEN1LMNA | |
| SCHEMBL6420788 | 0.80 | ALDH1A1 (0.53) | ERN1TLR2TLR1TLR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104962278-B | Palladium ion fluorescent probe, and preparation method and applications thereof | 华东理工大学 | 2017-01-11 | — | — | CN | disclosed |
| EP-1060263-B1 | METHOD AND COMPOSITIONS FOR DETECTING LUCIFERASE IN BIOLOGICAL SAMPLES | PACKARD INSTRUMENT CO INC (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1060263-A4 | METHOD AND COMPOSITIONS FOR DETECTING LUCIFERASE IN BIOLOGICAL SAMPLES | PACKARD INSTRUMENT CO INC (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6171809-B1 | DETECTING PRESENCE OF BOTH FIREFLY AND RENILLA LUCIFERASE BY FIRST ADDING MIXTURE TO MEASURE FIREFLY ENZYME THEN RENILLA ENZYME; INCLUDES COMPOUNDS SELECTED TO PRODUCE AN EXTENDED GLOW RATHER THAN FLASH LUMINESCENCE | PACKARD INSTRUMENT COMPANY | 2001-01-09 | — | — | US | disclosed |
| EP-1060263-A1 | METHOD AND COMPOSITIONS FOR DETECTING LUCIFERASE IN BIOLOGICAL SAMPLES | Packard Instrument Company, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999038999-A1 | METHOD AND COMPOSITIONS FOR DETECTING LUCIFERASE IN BIOLOGICAL SAMPLES | PACKARD INSTRUMENT COMPANY, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-4670421-A | ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| US-4318914-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4310545-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4305959-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4205085-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |
| US-3956113-A | REACTION PRODUCT OF CYANIDE, POSITIVE HALOGEN, AND POLYHYDROXY COMPOUNDS | MAX BRENNER, 33 SPIEGELBERGSTRASSE CH-4059 BASLES, (CH) | 1976-05-11 | — | — | US | disclosed |