Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413872 | 0.88 | MAPK1 (0.38) | LMNA | |
| SCHEMBL10550552 | 0.85 | NPC1 (0.41) | MEN1KMT2AHSD17B10 | |
| SCHEMBL10414278 | 0.84 | POLB (0.38) | MEN1LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL10413424 | 0.81 | KDM5A (0.30) | — | |
| SCHEMBL10413422 | 0.81 | KDM5A (0.30) | — | |
| SCHEMBL10413407 | 0.81 | HSD17B10 (0.33) | KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL10412840 | 0.80 | HSD17B10 (0.40) | KDM4EMEN1LMNAKMT2AHSD17B10 | |
| SCHEMBL10413410 | 0.80 | PREP (0.39) | — | |
| SCHEMBL10414814 | 0.79 | CYP3A4 (0.31) | KMT2AHSD17B10TDP1 | |
| SCHEMBL10414813 | 0.79 | CYP3A4 (0.31) | KMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |