Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413410 | 0.88 | PREP (0.39) | ALDH1A1 | |
| SCHEMBL10414816 | 0.88 | KDM4E (0.33) | LMNA | |
| SCHEMBL10414278 | 0.87 | POLB (0.38) | SLC22A8POLBALDH1A1LMNATSHR | |
| SCHEMBL10547616 | 0.84 | GAPDH (0.40) | ALDH1A1 | |
| SCHEMBL10413424 | 0.84 | KDM5A (0.30) | — | |
| SCHEMBL10414814 | 0.84 | CYP3A4 (0.31) | MAPK1CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL10548246 | 0.84 | GAPDH (0.40) | ALDH1A1 | |
| SCHEMBL10412840 | 0.83 | HSD17B10 (0.40) | MAPK1SLC22A8CYP2C19POLBALDH1A1 | |
| SCHEMBL10413407 | 0.82 | HSD17B10 (0.33) | ALDH1A1LMNATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL10414303 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |