Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414814 | 0.90 | CYP3A4 (0.31) | HSD17B10ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL10412836 | 0.90 | NR1I2 (0.32) | HSD17B10ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL10545815 | 0.85 | KMT2A (0.42) | HSD17B10ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL10413872 | 0.83 | MAPK1 (0.38) | ALDH1A1CYP3A4CYP2C19MAPK1LMNA | |
| SCHEMBL10413404 | 0.81 | MAPT (0.39) | HSD17B10TDP1MAPTKMT2AMEN1 | |
| SCHEMBL10414816 | 0.80 | KDM4E (0.33) | HSD17B10TDP1KMT2AKDM4EMEN1 | |
| SCHEMBL10917958 | 0.79 | ALDH1A1 (0.44) | HSD17B10ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL10414276 | 0.78 | TYMP (0.30) | — | |
| SCHEMBL10414809 | 0.78 | MEN1 (0.35) | HSD17B10TDP1MAPTKMT2AMEN1 | |
| SCHEMBL10414278 | 0.78 | POLB (0.38) | HSD17B10ALDH1A1TDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912214-A | Containing azelidin-2-one ring | HOFFMAN-LA ROCHE INC. (US) | 1990-03-27 | — | — | US | disclosed |