Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463876 | 0.76 | CA4 (0.32) | SMN1; SMN2L3MBTL1NPC1RAB9ATDP1 | |
| Diphenylether SCHEMBL10454819 | 0.65 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL218556 | 0.64 | GPR3 (0.35) | — | |
| SCHEMBL550941 | 0.64 | GPR3 (0.35) | SMN1; SMN2RAB9AMAPTALDH1A1 | |
| Diphenylether SCHEMBL14657075 | 0.63 | LTA4H (0.86) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL1718434 | 0.63 | LTA4H (0.86) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL9061108 | 0.62 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL4950525 | 0.62 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL2461810 | 0.62 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL12286 | 0.62 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161211-A1 | N-heterocyclosulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | claimed |
| US-4932997-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0161211-A1 | N-heterocyclosulfonyl-N'-pyrimidinyl and -triazinyl ureas | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |