Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657318 | 0.99 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL10417667 | 0.99 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL10415804 | 0.99 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL10488898 | 0.96 | DHFR (0.79) | DHFRHTT | |
| SCHEMBL10488971 | 0.88 | DHFR (0.81) | DHFRHTT | |
| SCHEMBL10488908 | 0.88 | DHFR (0.85) | DHFRHTT | |
| SCHEMBL11396054 | 0.88 | DHFR (0.72) | DHFRHTT | |
| Diaveridine SCHEMBL93896 | 0.88 | DHFR (1.00) | DHFRHTT | |
| Diaveridine SCHEMBL29527560 | 0.88 | DHFR (1.00) | DHFRHTT | |
| SCHEMBL11383945 | 0.85 | DHFR (0.72) | DHFRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231888-A2 | Substituted 2,4-diamino-5-benzyl pyrimidines, their preparation and their use as medicines having an antimicrobian activity | Fatol Arzneimittel GmbH (DE) | 1987-08-12 | — | — | EP | claimed |
| US-4912112-A | Substituted 2,4-diamino-5-benzylpyrimidines, their preparation and their use as medicaments with an antimicrobial activity | SAARSTICKSTOFF-FATOL GMBH CHEM.-PHARM. FABRIK (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0231888-A2 | Substituted 2,4-diamino-5-benzyl pyrimidines, their preparation and their use as medicines having an antimicrobian activity | Fatol Arzneimittel GmbH (DE) | 1987-08-12 | — | — | EP | disclosed |