Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.71 |
| ▸ | CSF1R | P07333 | 1/20 | 0.71 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.71 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaveridine SCHEMBL93896 | 0.90 | DHFR (1.00) | DHFRHTTNTRK1CSF1RNTRK3 | |
| Diaveridine SCHEMBL29527560 | 0.90 | DHFR (1.00) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL10488898 | 0.89 | DHFR (0.79) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL11397831 | 0.89 | DHFR (0.74) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL10416191 | 0.88 | DHFR (0.77) | DHFRHTT | |
| SCHEMBL10488908 | 0.88 | DHFR (0.85) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL10415804 | 0.87 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL10417667 | 0.87 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL9657318 | 0.87 | DHFR (0.76) | DHFRHTT | |
| SCHEMBL11383945 | 0.85 | DHFR (0.72) | DHFRHTTNTRK1CSF1RNTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883798-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY, ANTIANGINAL AND ANTIOXIDANT AGENT | EGIS GYOGYSZERGYAR (HU) | 1989-11-28 | — | — | US | claimed |
| US-4883798-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY, ANTIANGINAL AND ANTIOXIDANT AGENT | EGIS GYOGYSZERGYAR (HU) | 1989-11-28 | — | — | US | disclosed |
| EP-0301428-A2 | Benzyldiaminopyrimidine derivatives and their use as medicaments | EGIS GYOGYSZERGYAR (HU) | 1989-02-01 | — | — | EP | disclosed |