Diaveridine

Diaveridine

SCHEMBL93896

COc1ccc(Cc2cnc(N)nc2N)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 1.00
HTT P42858 1/20 1.00
NTRK1 P04629 1/20 0.77
CSF1R P07333 1/20 0.77
NTRK3 Q16288 1/20 0.77
NTRK2 Q16620 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diaveridine SCHEMBL29527560 1.00 DHFR (1.00) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL10488908 0.92 DHFR (0.85) DHFRHTTNTRK1CSF1RNTRK3
Diaveridine SCHEMBL11480370 0.91 DHFR (0.83) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL9830386 0.90 DHFR (0.82) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL10488971 0.90 DHFR (0.81) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL10488965 0.89 DHFR (0.79) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL10488898 0.89 DHFR (0.79) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL9657245 0.88 DHFR (0.78) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL9654048 0.88 DHFR (0.78) DHFRHTTNTRK1CSF1RNTRK3
SCHEMBL7126736 0.88 DHFR (0.78) DHFRHTTNTRK1CSF1RNTRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536217-A1 CO-AGENTS AS THERAPY AGAINST ANAEROBIC PATHOGENS Fleurir Abx LLC (US) 2025-04-16 EP claimed
US-20250076282-A1 Identification of Viable Human Embryos Overture Life, Inc. (US) 2025-03-06 US claimed
US-12181462-B2 Identification of viable human embryos Overture Life, Inc. (US) 2024-12-31 US claimed
US-20240293434-A1 COMBINATION THERAPY EFFECTIVE AGAINST MICROORGANISMS, INCLUDING DRUG RESISTANT MICROORGANISMS FLEURIR ABX LLC (US) 2024-09-05 US claimed
US-20230398101-A1 Co-agents as Therapy Against Anaerobic Pathogens FLEURIR ABX LLC (US) 2023-12-14 US claimed
WO-2023239822-A1 CO-AGENTS AS THERAPY AGAINST ANAEROBIC PATHOGENS FLEURIR ABX LLC (US) 2023-12-14 WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
US-20220169680-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2022-06-02 US claimed
EP-3999846-A1 IDENTIFICATION OF VIABLE HUMAN EMBRYOS Overture Life, Inc (US) 2022-05-25 EP claimed
EP-3912989-A1 CELL-PENETRATING PEPTIDE BASED ON INFLUENZA VIRUS M2 PROTEIN Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) 2021-11-24 EP claimed
US-6545033-B1 GABA receptor inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-04-08 US claimed
WO-2002096216-A1 A METHOD OF IMPROVING THE GROWTH PERFORMANCE OF AN ANIMAL THE UNIVERSITY OF SYDNEY (AU) 2002-12-05 WO claimed
WO-2002067979-A1 METHOD OF IMPROVING THE GROWTH PERFORMANCE OF AN ANIMAL THE UNIVERSITY OF SYDNEY (AU) 2002-09-06 WO claimed
US-6211185-B1 ADMINISTERING ORALLY WITH DRINKING WATER VETERINARY PHARMACY CORPORATION 2001-04-03 US claimed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 EP claimed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
US-4873249-A 2,4-DIAMINO-5-(3,4-DIMETHOXY-BENZYL)-PYRIMIDINE; ANALGESIC OR ANTINFLAMMATORY AGENT EGIS GYOGYSZERGYAR (HU) 1989-10-10 US claimed
US-4871722-A TRIMETOPRIM, DIAVERIDINE, SULFADIMETHOXINE, 8-HYDROXYQUINOLINE, AND/OR SALTS; POULTRY; ANTIBACTERIAL FEEDS EGIS GYOGYSZERGVAR (HU) 1989-10-03 US claimed
US-4133879-A Process for producing stable solutions of a sulphonamide and a potentiator AKTIESELSKABET ROSCO (DK) 1979-01-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293434-A1 COMBINATION THERAPY EFFECTIVE AGAINST MICROORGANISMS, INCLUDING DRUG RESISTANT MICROORGANISMS SLC11A2, MYD88, FPR2 DHFR 7/4885HTT 2861/4885NTRK1 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.