⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668190 | 0.72 | — | — | |
| SCHEMBL8990495 | 0.69 | LMNA (0.44) | — | |
| SCHEMBL10413306 | 0.69 | LMNA (0.44) | — | |
| SCHEMBL8769670 | 0.69 | LMNA (0.44) | — | |
| Hydrogen Sulfide SCHEMBL25252062 | 0.67 | — | — | |
| SCHEMBL27485685 | 0.63 | — | — | |
| SCHEMBL44994 | 0.63 | — | — | |
| SCHEMBL6837252 | 0.62 | — | — | |
| SCHEMBL5359711 | 0.59 | — | — | |
| SCHEMBL2992041 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015018855-A1 | PENTAFLUOROETHYLATING COMPOSITIONS | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ES) | 2015-02-12 | — | — | WO | claimed |
| EP-2835374-A1 | Pentafluoroethylating compositions | Fundació Institut Català d'Investigació Química (ES) | 2015-02-11 | — | — | EP | claimed |
| EP-3500257-B1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2025-07-02 | — | — | EP | disclosed |
| US-11066370-B2 | Kinase inhibitor compounds, compositions, and methods of treating cancer | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200325103-A1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2020-10-15 | — | — | US | disclosed |
| US-10519113-B2 | Kinase inhibitor compounds, compositions, and methods of treating cancer | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-12-31 | — | — | US | disclosed |
| CN-110072526-A | Kinase inhibitor compounds, compositions and methods for treating cancer | 西奈山伊坎医学院 | 2019-07-30 | — | — | CN | disclosed |
| US-20190202789-A1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICHAN SCHOOL OF MEDICINE AT MOUNT SINAL (US) | 2019-07-04 | — | — | US | disclosed |
| EP-3500257-A1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | Icahn School of Medicine at Mount Sinai (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-3319943-B1 | NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-10239859-B2 | Nitrogen-containing heterocycles as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-26 | — | — | US | disclosed |
| US-20180201600-A1 | NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | US | disclosed |
| EP-3319943-A1 | NITROGENOUS HETEROCYCLES AS A PESTICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-16 | — | — | EP | disclosed |
| WO-2018035346-A1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICHAN SCHOOL OF MEDICINE AT MOUNT SINAL (US) | 2018-02-22 | — | — | WO | disclosed |
| WO-2015018855-A1 | PENTAFLUOROETHYLATING COMPOSITIONS | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ES) | 2015-02-12 | — | — | WO | disclosed |
| EP-2835374-A1 | Pentafluoroethylating compositions | Fundació Institut Català d'Investigació Química (ES) | 2015-02-11 | — | — | EP | disclosed |
| US-4895991-A | FROM AROMATIC HALIDE, DIFLUORODIHALOMETHANE, COPPER, CHAIN EXTENSION SUPPRESSING HALIDE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4749802-A | REACTING COPPER WITH A DIFLUORODIHALOMETHANE | UNIVERSITY OF IOWA RESEARCH FOUNDATION, INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4650887-A | TRIFLUOROMETHYLCOPPER REAGENT | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1987-03-17 | — | — | US | disclosed |
| US-4582921-A | REACTING DIFLUORIDIHALOMETHANE WITH CADIUM OR ZINC IN APROTIC SOLVENT | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1986-04-15 | — | — | US | disclosed |