Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764371 | 0.93 | ADRB2 (0.41) | SLC2A1ADRB2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10418435 | 0.91 | CYP51A1 (0.43) | SLC2A1ADRB2CYP51A1KCNA5 | |
| SCHEMBL9764456 | 0.91 | ADRB2 (0.41) | SLC2A1ADRB2CYP51A1CYP1A2CYP3A4 | |
| SCHEMBL9764429 | 0.91 | ADRB2 (0.41) | SLC2A1ADRB2CYP51A1CYP1A2CYP3A4 | |
| SCHEMBL10389958 | 0.90 | ADRB2 (0.41) | SLC2A1ADRB2CYP51A1CYP3A4KDM4E | |
| SCHEMBL10416523 | 0.88 | SLC2A1 (0.41) | SLC2A1ADRB2CYP51A1CYP1A2CYP3A4 | |
| SCHEMBL10417001 | 0.88 | CYP51A1 (0.43) | SLC2A1ADRB2CYP51A1CYP3A4CYP2D6 | |
| SCHEMBL9764301 | 0.88 | NR1H3 (0.45) | ADRB2KCNH2TSHRBCHENR1H3 | |
| SCHEMBL9321535 | 0.86 | MAOB (0.37) | ADRB2CYP51A1CYP3A4KDM4EADRB1 | |
| SCHEMBL10417737 | 0.86 | SLC2A1 (0.39) | SLC2A1ADRB2CYP51A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937251-A | TREATING ASTHMA AND BRONCHITIS; ADRENERGIC STIMULANTS | GLAXO GROUP LIMITED (GB) | 1990-06-26 | — | — | US | disclosed |