Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417441 | 0.93 | CD274 (0.42) | CD274PTPN1HDAC1HDAC6PDCD1 | |
| SCHEMBL10417444 | 0.82 | PTPN1 (0.56) | CD274PTPN1HDAC8 | |
| SCHEMBL2544343 | 0.80 | CASP1 (0.46) | — | |
| SCHEMBL9331302 | 0.80 | CASP1 (0.46) | — | |
| SCHEMBL30122530 | 0.80 | CASP1 (0.46) | — | |
| SCHEMBL1420538 | 0.80 | CASP1 (0.46) | — | |
| SCHEMBL30904667 | 0.80 | CASP1 (0.46) | — | |
| SCHEMBL30863677 | 0.79 | MDM2 (0.49) | PTPN1 | |
| SCHEMBL10418082 | 0.79 | MDM2 (0.49) | PTPN1 | |
| SCHEMBL23118169 | 0.79 | ITGB3 (0.48) | PTPN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935536-A | TRIALKOXYBENZYL PROTECTED AMINO ACID | MILLIPORE CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0292228-A2 | Protecting groups for asparagine and glutamine in peptide synthesis | MILLIPORE CORPORATION (US) | 1988-11-23 | — | — | EP | disclosed |