Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420194 | 0.88 | MAPT (0.33) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL10337040 | 0.87 | MAPT (0.53) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL10418850 | 0.85 | MAPT (0.46) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL2397763 | 0.82 | MAPT (0.54) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL2401836 | 0.73 | KDM4E (0.44) | MAPTLMNAGAANPSR1RECQL | |
| SCHEMBL2007471 | 0.73 | HIF1A (0.45) | MAPTLMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL8717639 | 0.73 | KDM4E (0.43) | MAPTLMNAGAANPSR1RECQL | |
| SCHEMBL8680627 | 0.72 | MAPT (0.49) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL29848328 | 0.70 | MAPT (0.63) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL29931020 | 0.70 | MAPT (0.63) | MAPTLMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931220-A | EMULSION POLYMERIZATION OF POLYFUNCTIONAL ACRYLATE MIXED WITH PIGMENT; POWDERS | PPG INDUSTRIES, INC. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4880667-A | SUNGLASSES, SPIROINDOLINE PHOTOCHROMIC COMPOUND | PPG INDUSTRIES, INC. (US) | 1989-11-14 | — | — | US | disclosed |