SCHEMBL2401836

SCHEMBL2401836

CCC1(C)c2cc(C)c(C)cc2N(C)C12C=Nc1c(ccc3ncccc13)O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.44
MAPT P10636 4/20 0.44
THRB P10828 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALOX12 P18054 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
PKM P14618 1/20 0.44
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2397763 0.88 MAPT (0.54) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL5859725 0.85 MAPT (0.61) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL10668944 0.84 KDM4E (0.41) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL10420194 0.84 MAPT (0.33) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL8717639 0.82 KDM4E (0.43) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL29493000 0.77 MAPT (0.72) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL7117468 0.77 MAPT (0.72) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL10668429 0.76 MAPT (0.48) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL14902888 0.74 MAPT (0.43) KDM4EMAPTTHRBSMN1; SMN2ALOX12
SCHEMBL10552518 0.74 MAPT (0.55) KDM4EMAPTTHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7033581-B2 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2006-04-25 US claimed
EP-1424918-B1 METHOD OF TREATING HAIR WITH HEAT AND A CAP WHICH PROVIDES A SIGNAL REGARDING TREATMENT UNILEVER PLC (GB) 2005-11-23 EP claimed
US-20050074639-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-04-07 US claimed
US-20030030040-A1 Reversibly variable photochromic color composition for articles composed of synthetic resin LUTHERN JOHN JOSEPH (US) 2003-02-13 US claimed
EP-0141407-B1 PHOTOCHROMIC COMPOUND AND ARTICLES CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1988-06-15 EP claimed
EP-0141407-A2 Photochromic compound and articles containing the same PPG INDUSTRIES, INC. (US) 1985-05-15 EP claimed
EP-1404768-B1 POLYURETHANE BASED BALLPOINT INKS BIC CORP (US) 2020-04-22 EP disclosed
US-10249693-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20140231780-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
US-8729793-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2014-05-20 US disclosed
US-8508121-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-13 US disclosed
EP-1394595-B1 PLASTIC MOLDED PRODUCT HAVING PHOTOCHROMIC CHARACTERISTICS AND/OR POLARIZING CHARACTERISTICS MITSUBISHI GAS CHEMICAL CO (JP) 2013-05-01 EP disclosed
US-20110291552-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2011-12-01 US disclosed
US-20020197484-A1 Transparent synthetic resin laminate having photochromism MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-12-26 US disclosed
US-20020122780-A1 Photochromic hair coloring composition DRAGOCO GERBERDING & CO AG (DE) 2002-09-05 US disclosed
EP-1090977-A2 Color changing candle Dragoco Gerberding & Co Aktiengesellschaft (DE) 2001-04-11 EP disclosed
US-5431697-A Reversibly variable color patterning composition for synthetic resin articles MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1995-07-11 US disclosed
US-5208132-A Microencapsulation of hindered amines MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-05-04 US disclosed
EP-0480162-A1 Dyeing method and dyed product MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1992-04-15 EP disclosed
US-4880667-A SUNGLASSES, SPIROINDOLINE PHOTOCHROMIC COMPOUND PPG INDUSTRIES, INC. (US) 1989-11-14 US disclosed