Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973495 | 0.94 | CTSL (0.56) | C5AR1MC4RCTSLCTSSCTSK | |
| SCHEMBL29476471 | 0.92 | C5AR1 (0.50) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29973259 | 0.92 | GLP1R (0.52) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30510367 | 0.92 | MC4R (0.52) | C5AR1MC4RCTSLCTSSCTSK | |
| SCHEMBL29511062 | 0.91 | MC4R (0.51) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30037518 | 0.90 | IL23R (0.53) | MC4RCTSLCTSSCTSKCTSH | |
| SCHEMBL1371627 | 0.90 | C5AR1 (0.56) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1371631 | 0.90 | C5AR1 (0.56) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30118069 | 0.89 | C5AR1 (0.52) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29666221 | 0.89 | C5AR1 (0.52) | C5AR1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950651-A | Leukemia; antitumer agents | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1990-08-21 | — | — | US | disclosed |
| EP-0078167-B1 | NEW N-NITROSO-N-(BETA-CHLORO-ETHYL)-CARBAMOYL PEPTIDES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-02-03 | — | — | EP | disclosed |
| EP-0078167-A1 | New N-nitroso-N-(beta-chloro-ethyl)-carbamoyl peptides | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1983-05-04 | — | — | EP | disclosed |