SCHEMBL30037518

SCHEMBL30037518

N=C(N)NCCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 3/20 0.53
▸ MC4R P32245 2/20 0.52
▸ CCKBR P32239 6/20 0.50
▸ GLP1R P43220 2/20 0.49
▸ CTSL P07711 3/20 0.49
▸ CTSS P25774 3/20 0.49
▸ CTSK P43235 3/20 0.49
▸ CTSH P09668 1/20 0.49
▸ CCKAR P32238 2/20 0.49
▸ OPRD1 P41143 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037495 0.94 MC4R (0.52) IL23RMC4RCCKBRCTSLCTSS
SCHEMBL10419744 0.90 C5AR1 (0.51) MC4RGLP1RCTSLCTSSCTSK
SCHEMBL30264577 0.89 MC4R (0.52) IL23RMC4RCTSLCTSSCTSK
SCHEMBL31016486 0.89 CTSL (0.55) IL23RMC4RCCKBRGLP1RCTSL
SCHEMBL30510367 0.88 MC4R (0.52) MC4RCCKBRCTSLCTSSCTSK
SCHEMBL30464987 0.88 IL23R (0.57) IL23RMC4RCCKBRCCKAROPRD1
SCHEMBL30599231 0.87 QRFPR (0.47) IL23RMC4RCTSLCTSSCTSK
SCHEMBL14117706 0.87 MC4R (0.55) IL23RMC4RCCKBRCTSLCTSS
SCHEMBL21146569 0.87 IL23R (0.66) IL23RMC4R
SCHEMBL31016482 0.86 CTSL (0.54) IL23RGLP1RCTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US claimed
EP-4347019-A1 MC3R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-04-10 — — EP claimed
WO-2022251650-A1 MC3R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-12-01 — — WO claimed
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US disclosed
EP-4347019-A1 MC3R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-04-10 — — EP disclosed
WO-2022251650-A1 MC3R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-12-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287154-A1 MC3R AGONIST PEPTIDES MC3R, MC4R, MC1R IL23R 466/4885MC4R 2/4885CCKBR 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback