SCHEMBL10419792

SCHEMBL10419792

CC(C)Oc1cc(N2C(=O)[C@@H](C)[C@@H](C)C2=O)c(F)cc1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 11/20 0.54
MEN1 O00255 1/20 0.40
NR1I2 O75469 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10419793 1.00 PPOX (0.54) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL10620814 0.84 PPOX (0.75) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL10419790 0.82 PPOX (0.55) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9620064 0.80 PPOX (0.48) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9590439 0.78 PPOX (0.52) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL8084286 0.77 PPOX (0.69) PPOX
SCHEMBL9619999 0.77 PPOX (0.47) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL10583469 0.76 PPOX (0.50) PPOXMEN1NR1I2KMT2ATDP1
SCHEMBL9804968 0.76 PPOX (0.53) PPOX
SCHEMBL9834941 0.76 PPOX (0.52) PPOXMEN1NR1I2KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929272-A N-phenyl-maleimides and N-phenyl-succinimides and their use in a herbicidal and/or plant growth regulating action CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4804400-A PRE- AND POSTEMERGENCE; GRAINS CIBA-GEIGY CORPORATION (US) 1989-02-14 US disclosed