Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.64 |
| ▸ | MMP2 | P08253 | 8/20 | 0.64 |
| ▸ | MMP3 | P08254 | 8/20 | 0.64 |
| ▸ | PDE4A | P27815 | 8/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.64 |
| ▸ | MMP13 | P45452 | 7/20 | 0.57 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420615 | 0.95 | MMP1 (0.58) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10419183 | 0.95 | MMP1 (0.58) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10420879 | 0.91 | MMP1 (0.54) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10420220 | 0.91 | MMP1 (0.54) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10420433 | 0.91 | MMP1 (0.54) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10420789 | 0.90 | MMP2 (0.53) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10419478 | 0.90 | MMP2 (0.53) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL9858267 | 0.89 | MMP1 (0.52) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10420420 | 0.87 | TRPA1 (0.48) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL10419552 | 0.87 | TRPA1 (0.48) | MMP1MMP2MMP3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |