Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP7 | P09237 | 1/20 | 0.58 |
| ▸ | MMP14 | P50281 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183052 | 0.80 | KDM1A (0.48) | MMP2MMP7MAPTEEF2KCA1 | |
| SCHEMBL941038 | 0.80 | ALDH1A1 (0.54) | MMP2MMP7MMP14MAPTCA1 | |
| SCHEMBL28478771 | 0.79 | FFAR1 (0.62) | MMP2MMP7MMP14FFAR1 | |
| SCHEMBL2338967 | 0.79 | MAPT (0.58) | MMP2FFAR1MAPTKEAP1NFE2L2 | |
| SCHEMBL1981537 | 0.76 | MMP2 (0.66) | MMP2MMP7MMP14FFAR1CA2 | |
| SCHEMBL506270 | 0.76 | MAPT (0.55) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL6203735 | 0.76 | RECQL (0.66) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL6319697 | 0.76 | GSK3B (0.53) | CA1CA2MAOAMAOB | |
| SCHEMBL270706 | 0.76 | MMP2 (0.77) | MMP2MMP7MMP14 | |
| SCHEMBL1014212 | 0.76 | CA2 (0.58) | MAPTCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |