Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361690 | 0.89 | PPARG (0.52) | PPARGPPARAGGT1PLAAT3PLAAT5 | |
| SCHEMBL31661910 | 0.84 | TLR2 (0.55) | PPARGPPARAFOLH1TLR2ALDH1A1 | |
| SCHEMBL10419542 | 0.83 | PPARA (0.47) | PPARGPPARAGGT1FOLH1PLAAT3 | |
| SCHEMBL12292601 | 0.82 | FOLH1 (0.51) | PPARGPPARAFOLH1TLR2ALDH1A1 | |
| SCHEMBL10419412 | 0.81 | ALB (0.56) | PPARGPPARAFOLH1HDAC1 | |
| SCHEMBL10419471 | 0.81 | MMP8 (0.54) | PPARGPPARAPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11342559 | 0.80 | ADAMTS5 (0.56) | PPARGPPARAALDH1A1LMNA | |
| SCHEMBL11344065 | 0.80 | ADAMTS5 (0.56) | PPARGPPARAALDH1A1LMNA | |
| SCHEMBL894883 | 0.80 | FOLH1 (0.49) | GGT1FOLH1ALDH1A1LMNAMEN1 | |
| SCHEMBL10482542 | 0.80 | MME (0.56) | GGT1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |