Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421834 | 0.92 | PDK1 (0.40) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10420210 | 0.79 | PDK1 (0.38) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10420623 | 0.79 | PDK1 (0.37) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL4652737 | 0.78 | MAPT (0.54) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL9870968 | 0.78 | PDK1 (0.52) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10421656 | 0.78 | KMT2A (0.47) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL13592955 | 0.75 | PDK1 (0.40) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL9869447 | 0.75 | PDK1 (0.49) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL239425 | 0.75 | PDK1 (0.40) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL28829630 | 0.73 | MAPT (0.49) | MEN1KMT2AHTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0197756-A2 | Alkanoyl anilides | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197451-A2 | Energy submetering system | HONEYWELL INC. (US) | 1986-10-15 | — | — | EP | disclosed |