Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420626 | 0.92 | PDK1 (0.48) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10420241 | 0.84 | MAPT (0.57) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL9870149 | 0.84 | GAA (0.54) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL10420192 | 0.84 | PDK1 (0.61) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL9869867 | 0.84 | ALDH1A1 (0.55) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL9869441 | 0.84 | PDK1 (0.51) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10420550 | 0.82 | PDK1 (0.76) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL10421645 | 0.81 | RECQL (0.52) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10421643 | 0.80 | PDK1 (0.45) | PDK1PDK2PDK3PDK4ABCC9 | |
| SCHEMBL10579820 | 0.80 | CXCR1 (0.57) | MEN1KMT2AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| US-4962284-A | HERBICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| US-4826841-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0197756-A2 | Alkanoyl anilides | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |