Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20981707 | 0.90 | NHERF1 (0.67) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL7782225 | 0.89 | NHERF1 (0.76) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL5925553 | 0.87 | MAPT (0.72) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL13028451 | 0.87 | NHERF1 (0.73) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL28280869 | 0.85 | NHERF1 (0.71) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL8074273 | 0.84 | MAPT (0.67) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL5184903 | 0.84 | KMT2A (0.69) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL17331309 | 0.84 | TCF4 (0.79) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL16672108 | 0.82 | LMNA (0.63) | NHERF1KMT2AGAALMNAMEN1 | |
| SCHEMBL23141046 | 0.82 | KMT2A (0.59) | NHERF1KMT2AGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940713-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0341837-A2 | Glutamic acid derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |
| US-4211883-A | Process for the production of p-(N-methyl)-aminobenzoyl-L-glutamic acid | LONZA, LTD. (CH) | 1980-07-08 | — | — | US | disclosed |