Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.66 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.66 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020804 | 0.91 | ADORA2A (0.56) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| Hydrochloric Acid SCHEMBL7027309 | 0.89 | ADORA2A (0.55) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL9546979 | 0.82 | SIRT1 (0.68) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL1063544 | 0.82 | SIRT1 (0.68) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL27713795 | 0.79 | SIRT1 (0.68) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL7282937 | 0.78 | ADORA1 (0.65) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL7318202 | 0.78 | ADORA2B (1.00) | ADORA1ADORA2B | |
| SCHEMBL7497485 | 0.77 | SIRT1 (0.61) | SIRT1SIRT3SIRT5ADORA1 | |
| SCHEMBL9708416 | 0.77 | ADORA1 (0.71) | SIRT1SIRT3SIRT5ADORA1ADORA2B | |
| SCHEMBL10728469 | 0.77 | ADORA2A (0.62) | SIRT1SIRT3SIRT5ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968672-A | DRUG DELIVERY; DIURETICS, KIDNEY DISORDERS, HYPOTENSIVE AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1990-11-06 | — | — | US | disclosed |