Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619112 | 0.84 | HMGB1 (0.59) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31617745 | 0.83 | HTT (0.56) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL534811 | 0.83 | HTT (0.56) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL668837 | 0.82 | MRGPRX4 (0.56) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL39623 | 0.81 | HMGB1 (0.65) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29695710 | 0.81 | HMGB1 (0.65) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21121083 | 0.81 | MGLL (0.46) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7937089 | 0.80 | GABRA1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10PRKCE | |
| SCHEMBL10421199 | 0.80 | HMGB1 (0.48) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27360496 | 0.79 | HMGB1 (0.62) | HMGB1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101941909-B | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2013-03-13 | — | — | CN | claimed |
| CN-109836351-A | A kind of preparation method of cholagogic alibendol | 辽宁博美医药科技有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109836351-A | A kind of preparation method of cholagogic alibendol | 辽宁博美医药科技有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-108430994-A | Compound, composition and method for adjusting CFTR | 蛋白质平衡治疗股份有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-101941909-B | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2013-03-13 | — | — | CN | disclosed |
| CN-101941909-B | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2013-03-13 | — | — | CN | disclosed |
| CN-101941909-B | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2013-03-13 | — | — | CN | disclosed |
| CN-102898384-A | Intermediate for preparing gefitinib and preparation method of | DENG LILI | 2013-01-30 | — | — | CN | disclosed |
| CN-101941909-A | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2011-01-12 | — | — | CN | disclosed |
| CN-101941909-A | Preparation method for 2-hydroxy-3-methoxy-methyl benzoate | UNIV NANCHANG | 2011-01-12 | — | — | CN | disclosed |