Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710323 | 0.85 | EPHX1 (0.35) | TP53NPSR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10701343 | 0.79 | ALDH1A1 (0.42) | TP53ALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL10712271 | 0.75 | ALDH1A1 (0.37) | TP53ALDH1A1SMN1; SMN2EPHX1CA12 | |
| SCHEMBL8283254 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL22143669 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL24724891 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL2608454 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL4570295 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL954821 | 0.74 | DPP4 (0.47) | TP53NPSR1ALDH1A1SLC6A3THRB | |
| SCHEMBL13150879 | 0.74 | TP53 (0.43) | KMT2AMEN1TP53NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |