Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421627 | 0.85 | KMT2A (0.42) | EPHX1TP53SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10701343 | 0.78 | ALDH1A1 (0.42) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL10712271 | 0.77 | ALDH1A1 (0.37) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL8895979 | 0.72 | METAP2 (0.45) | EPHX1SMN1; SMN2METAP2 | |
| SCHEMBL27811075 | 0.72 | EPHX1 (0.42) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL7317494 | 0.72 | TP53 (0.42) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1986462 | 0.71 | EPHX1 (0.40) | EPHX1TP53KDM4ESMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL9744757 | 0.71 | ALDH1A1 (0.37) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL10595888 | 0.71 | CYP2D6 (0.41) | ALDH1A1NPSR1METAP2TSHR | |
| SCHEMBL882633 | 0.70 | TSHR (0.40) | KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |