Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421189 | 0.86 | MRGPRX4 (0.58) | RXRARXRBRXRGHMGB1CXCL12 | |
| SCHEMBL10420839 | 0.83 | RXRA (0.63) | RXRARXRBRXRGKDM4CFFAR4 | |
| SCHEMBL10422128 | 0.79 | HMGB1 (0.58) | HMGB1CXCL12KDM4CPOLBMCL1 | |
| SCHEMBL13965398 | 0.77 | MEN1 (0.56) | HMGB1CXCL12MCL1MEN1KMT2A | |
| SCHEMBL6369577 | 0.77 | HMGB1 (0.73) | HMGB1CXCL12KMT2ACYP2C9KDM4E | |
| SCHEMBL29688181 | 0.76 | HMGB1 (0.83) | HMGB1CXCL12KMT2ACYP2C9KDM4E | |
| SCHEMBL1129138 | 0.76 | HMGB1 (0.83) | HMGB1CXCL12KMT2ACYP2C9KDM4E | |
| Acetic Acid SCHEMBL28238681 | 0.76 | RXRA (0.73) | RXRARXRBRXRGFFAR4PTGER1 | |
| SCHEMBL5291219 | 0.75 | HTT (0.68) | RXRARXRBRXRGKDM4CPTGER1 | |
| SCHEMBL28346227 | 0.74 | RXRA (0.56) | RXRARXRBRXRGFFAR4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918047-A | CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0253666-A2 | Heat-sensitive recording material containing dye-forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |