Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054673 | 0.85 | TSHR (0.49) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL28061000 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL10422278 | 0.83 | HSD17B10 (0.53) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL2904566 | 0.81 | MAPK1 (0.48) | TDP1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10422347 | 0.80 | TSHR (0.60) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL30730905 | 0.78 | TSHR (0.40) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL16335619 | 0.77 | MAPT (0.50) | TSHRSMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3030569 | 0.77 | ALDH1A1 (0.53) | TSHRTDP1ALDH1A1HSPB1MEN1 | |
| SCHEMBL2902627 | 0.77 | MERTK (0.58) | TDP1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10422274 | 0.76 | HSD17B10 (0.58) | TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H726-H | HAIR DYES | CLAIROL INCORPORATED (US) | 1990-01-02 | — | — | US | disclosed |