Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22588392 | 0.86 | EPAS1 (0.37) | TSHRSMN1; SMN2HPGDPOLBALDH1A1 | |
| SCHEMBL22588128 | 0.80 | MEN1 (0.51) | TSHRSMN1; SMN2HPGDHSD17B10MAPT | |
| SCHEMBL22588389 | 0.80 | PIN1 (0.51) | SMN1; SMN2HPGDMAPTPOLBALDH1A1 | |
| SCHEMBL22588477 | 0.79 | L3MBTL1 (0.58) | TSHRSMN1; SMN2HPGDMAPTALDH1A1 | |
| SCHEMBL10422388 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2HSD17B10POLBALDH1A1 | |
| SCHEMBL22588393 | 0.77 | MERTK (0.48) | SMN1; SMN2HPGDMAPTPOLBALDH1A1 | |
| SCHEMBL624089 | 0.75 | TSHR (0.42) | TSHRSMN1; SMN2HSD17B10MAPTALDH1A1 | |
| SCHEMBL29671003 | 0.75 | TSHR (0.42) | TSHRSMN1; SMN2HSD17B10MAPTALDH1A1 | |
| SCHEMBL693936 | 0.72 | MAPT (0.40) | TSHRSMN1; SMN2HSD17B10MAPTALDH1A1 | |
| SCHEMBL3060390 | 0.71 | VCAM1 (0.46) | TSHRALDH1A1MAPK1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642399-A | Pyrrolopyridone derivatives useful for the treatment of cancer | 泰治疗有限公司 | 2024-03-01 | — | — | CN | disclosed |